Thermogenic capacity of human periaortic adipose tissue is transformed by body weight
Fig 6
Expression of thermogenic proteins in periaortic adipose tissue (PAT) and correlation with body mass index (BMI).
Based on the data in Fig 5, and the clinical data of patients a Pearson’s correlation analysis between the expression of thermogenic proteins and Body fat % estimation was carried out. Body Fat estimation was calculated by CUN-BAE method [19]. PPARg coactivator 1 alpha (PGC-1a) in male (r = -0.48 p<0.04) and female (r = -0.63, p<0.05) and TFAM in male (r = -0.72, p<0.0008) and female (r = -0.86, p<0.002) decreased significantly with progressive weight gain.