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Circulating small non-coding RNAs reflect IFN status and B cell hyperactivity in patients with primary Sjögren’s syndrome

Fig 2

RT-qPCR data of all nine sncRNAs included in the validation phase.

Serum sncRNAs were measured using single Taqman qRT-PCR in the validation cohort (n = 45). ΔCt per sample was calculated using the expression of an exogenous spiked-in Arabidopsis thaliana miRNA to correct for technical variation. The relative expression of each sample was calculated as fold change (FC) in comparison with the ΔCt mean of the HC group in the respective cohort. Medians ± IQR are shown.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0193157.g002