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Nanoparticle effect on neutrophil produced myeloperoxidase

Fig 2

The effect of nanoparticle on secreted MPO in protein rich media.

A- PS-COOH NPs; B- PS-NH2 NPs; C- PS-OSO3 or TiO2 NPs, as indicated. The supernatants from activated neutrophils were analyzed for MPO activity. The results are reported as % of MPO activity in samples without added nanoparticles in protein rich media. The results are a mean of three separate experiments each done in duplicates. p< 0,05 for all concentration of nanoparticles versus 0,1 mg/ml, expect for enzyme activity in presence of TiO2 which is not significantly different for all TiO2 concentration* p<0.05 versus activity in presence of 220nm COOH NPs. #p<0.05 versus activity in presence of 120 nm NPs. ● p<0.05 versus activity in presence of 26 nm, 60 nm, 220nm COOH NPs, 120 nm NH2 NPs and TiO2 NPs at 1, 0.5, 0.25 mg/ml.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0191445.g002