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Diagnostic markers for the detection of ovarian cancer in BRCA1 mutation carriers

Fig 2

Sensitivity and specificity.

Sensitivity and specificity of the combination of five biomarkers (CA125, MIF, Leptin, HE4, OPN) in differentiating between healthy women and OC patients (A), healthy wildtype women and wildtype OC patients (B), healthy BRCA1 mutation carriers and BRCA1 mutation carriers with OC (C), healthy wildtype women and healthy BRCA1 mutation carriers (D) and wildtype OC patients and BRCA1 mutation carriers with OC (E).

Fig 2

doi: https://doi.org/10.1371/journal.pone.0189641.g002