Fatty acids rather than hormones restore in vitro angiogenesis in human male and female endothelial cells cultured in charcoal-stripped serum
Fig 5
Palmitic acid and acetate rescue the CSS-induced inhibition of cell number.
Cell number was measured in F-ECs (A, orange bars) and M-ECs (B, blue bars) after 48h of incubation in SM (solid bars), CSS-M + vehicle (ethanol/BSA, cross-hitched bars), CSS-M + palmitic acid (250 μM, vertical bars), CSS-M (open bars), or CSS-M + acetate (20 mM, horizontal bars). In (A) and (B), **p<0.01 (CSS-M vs SM), *p<0.05 (CSS-M vs CSS-M + palmitic or CSS-M + acetate), n = 3–4 for F- and M-ECs, respectively, t test.