Impact of maternal high fat diet on hypothalamic transcriptome in neonatal Sprague Dawley rats
Fig 3
HFD offspring are significantly heavier at (A) PN1, (B) PN5 and (C) PN10. (D) HFD offspring are significantly longer compared with CON offspring. (E) HFD offspring display increased percentage of fat mass (relative to lean mass). (F) Total water was unchanged. (G) HFD offspring have increased blood glucose at PN10 compared to CON offspring. (H) HFD offspring have increased plasma leptin at PN10 compared to CON offspring. Maternal high fat diet offspring (HFD-O) = filled bars, maternal CON offspring (CON-O) = unfilled bars. P values from 2-way mixed model ANOVA analyses. Data represent mean± SEM. CON-O (n = 6), HFD-O (n = 11) except for blood glucose and plasma leptin CON-O (n = 6) and HFD-O (n = 6). M = male, F = female.