GNB3 overexpression causes obesity and metabolic syndrome
Fig 1
Transgenic GNB3 is highly expressed in the brain, at levels greater than endogenous Gnb3.
A. Transgenic human GNB3 and mouse endogenous Gnb3 gene expression in brain tissues of 5-week-old mice. B. GNB3 and Gnb3 expression in gWAT, iWAT, and BAT of 20-week-old mice. n = 4 mice per group in A, n = 3 mice per group in B. 3 technical replicates for both. Ct, cycle threshold.