Promising new vaccine candidates against Campylobacter in broilers
Fig 3
Anti-Campylobacter IgY antibodies in sera and Campylobacter loads in chicken ceca after DNA vaccination alone or protein vaccination alone and challenged using the YP9817 antigen.
Birds were vaccinated with the DNA vaccine alone on day 5 or with proteins alone on day 12 and then infected on day 19. (A) The IgY levels in blood samples were assessed by ELISAs each week until the end of the experiment on day 42 ± 1 day (data from day 1 to day 14 not shown). Each dot corresponds to the OD of an individual chicken. Bars represent the medians for each group. (B) Campylobacter counts were evaluated at the end of the experiment from ceca samples by qPCR (Log GenEq/g). The detection limit was set at 1.88 log10 GenEq/g. Samples with counts under the threshold were set at 0.94 log10 GenEq/g. No significant differences were observed between groups.