Increased soluble IL-7 receptor concentrations associate with improved IL-7 therapy outcomes in SIV-infected ART-treated Rhesus macaques
Fig 6
Plasma sCD127 concentrations associated with IL-7-induced activation of CD4+ T-cells in SIV-infected, ART-treated Rhesus macaques.
These effects were observed frequently among animals in this study, yet varied by IL-7 treatment cluster (depicted by arrows). (A-D) Increases of sCD127 paralleled the changes in Ki67+CD4+ TN and TCM cell numbers in 3 out of 4 animals evaluated, specifically (A) RM22657, (B) RM23686 and (C) RM23750.