Increased soluble IL-7 receptor concentrations associate with improved IL-7 therapy outcomes in SIV-infected ART-treated Rhesus macaques
Fig 5
Increased plasma sCD127 concentrations correlated with IL-7-induced increases in CD8+ T-cell subsets in SIV-infected Rhesus macaques.
All CD8+ T-cell subsets with statistically significant correlations with sCD127 are graphed here. Increasing concentrations of plasma sCD127 following IL-7 administration were positively correlated with increases in (A) total, (B) naïve TN, (C) transitional effector memory TTrM and (D) central memory TCM CD8+ T-cell subsets in SIV-infected, ART-treated Rhesus macaques (Spearman correlation analysis, r- and p-values are indicated on graphs).