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Adenosine, lidocaine and Mg2+ (ALM) fluid therapy attenuates systemic inflammation, platelet dysfunction and coagulopathy after non-compressible truncal hemorrhage

Fig 1

Schematic of the in vivo rat model of truncal bleeding and shock treated with two-phase resuscitation therapy.

Animals were anesthetized and mechanically ventilated for the entire experimental and monitoring period (~7 hr 15 min). Body temperature was allowed to drift after anesthesia.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0188144.g001