Hepatic Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) regulates metabolism in mice
Fig 5
Hepatocyte HIF1-α and hepatocyte HIF2-α deletion have no effects on metabolism in mice on chow diet.
Results for floxed controls (FC) are shown in black and LHIF1 or LHIF2 in white circles. (A) Glucose tolerance in LHIF mice at 16 weeks. (B) Pyruvate tolerance in LHIF mice at 18 weeks. (C) Insulin tolerance test in LHIF mice at 19 weeks. (D) Glucose tolerance in LHIF2 mice. (E) Pyruvate challenge in LHIF2 mice. Mean±SEM is shown, N = 4-5/group.