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Application and interpretation of functional data analysis techniques to differential scanning calorimetry data from lupus patients

Fig 2

A test for the difference in thermogram profiles between cases and controls.

The red line is the observed test statistic at a given temperature, while the dotted blue line is the pointwise critical value determined using 200 permutations. A test for overall differences in the curves between cases and controls can be done by comparing the maximum of the observed statistics (here, 14.22 at a temperature of 65.2°C) with the corresponding critical value for this maximum (dashed blue line).

Fig 2

doi: https://doi.org/10.1371/journal.pone.0186232.g002