Distinct and common expression of receptors for inflammatory mediators in vagal nodose versus jugular capsaicin-sensitive/TRPV1-positive neurons detected by low input RNA sequencing
Fig 3
RNA sequencing revealed distinct expression of transcription factors between nodose and jugular C-fiber neurons.
(A) Transcription factors differentially expressed in nodose and jugular C-fiber neurons from the Trpv1 selection. Y-axis indicates average of normalized counts per million (CPM) from Trpv1-tdTomato selection. Blue indicates nodose, red indicates jugular C-fiber neurons. P values were calculated based on group comparison. * p value ≤ 0.05; ** p value ≤ 0.01; *** p value ≤ 0.001. (B) Transcription factors differentially expressed in nodose and jugular C-fiber neurons from the capsaicin selection. Y-axis indicates average CPM from capsaicin selection. Blue indicates nodose, red indicates jugular C-fiber neurons. P values were calculated based on group comparison. * p value ≤ 0.05; ** p value ≤ 0.01; *** p value ≤ 0.001.