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Low-intensity pulsed ultrasound enhances angiogenesis and ameliorates contractile dysfunction of pressure-overloaded heart in mice

Fig 2

The LIPUS therapy ameliorates cardiac contractile dysfunction.

(A) Representative echocardiographic images at 8 weeks after TAC. (B~G) Graphs showing the time course of anterior wall thickness (AWT) and posterior wall thickness (PWT) of the LV, LV dimension at end-diastole (LVDd), LVD at end-systole (LVDs), LV fractional shortening (LVFS), and LV ejection fraction (LVEF). Results are expressed as mean±SD. n.s., not statistically significant. Statistical analysis was performed at 8 weeks after TAC.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0185555.g002