Simulation framework for generating intratumor heterogeneity patterns in a cancer cell population
Fig 10
Effect of cell death and migration on the 3D structures of simulated tumors for push methods 1–4 under constant-rate, step-function, and linear-function models.
k = ∞ is assumed. Descendants of the first four cells in each simulation run are presented in blue, green, yellow, and red. The results of three independent runs are shown for each setting.