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The species origin of the serum in the culture medium influences the in vitro toxicity of silica nanoparticles to HepG2 cells

Fig 5

Real-time cell index (CI) monitoring of HepG2 cells (n = 3) exposed to A) 50 μg/mL, B) 100 μg/mL M-MSNs, in a pristine state or covered with serum proteins, for 115 hours.

All curves represent the mean of three curves with recorded standard deviations at each time-point. The black arrow represents the starting point of exposure. Cell index was normalized to baseline (control cells).

Fig 5

doi: https://doi.org/10.1371/journal.pone.0182906.g005