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Flow velocity-driven differentiation of human mesenchymal stromal cells in silk fibroin scaffolds: A combined experimental and computational approach

Fig 4

Biochemical assay data at week 6 of culture.

Data of the vlow and vhigh group is expressed as fold change compared to the data of the static group. (A) Metabolic activity per cell. (B) DNA amount. (C) Osteogenic differentiation (represented in alkaline phosphatase (ALP) activity). *p<0.05 between vlow and vhigh, ¥p<0.05 between vlow or vhigh and the static group. N = 3 perfusion groups, N = 4 static group.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0180781.g004