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Simulated space radiation-induced mutants in the mouse kidney display widespread genomic change

Fig 5

Genomic LOH in Fe ion-induced mutants.

A. Percentage of Aprt mutants exhibiting genomic LOH at each dose tested. See text for more details. B. Percentage of Aprt mutants exhibiting genomic LOH that did not lose Aprt expression via chromosome loss. See text for more details. Asterisk (*) indicates significant difference relative to control (p<0.05). See Table 4.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0180412.g005