Immunohistochemical identification of Propionibacterium acnes in granuloma and inflammatory cells of myocardial tissues obtained from cardiac sarcoidosis patients
Fig 2
Representative samples with massive inflammatory foci.
Specimens obtained from autopsy samples in patients with CS (A–C), myocarditis (D–F), or other cardiomyopathy (G-I) were stained by haematoxylin and eosin and immunostained with anti-P. acnes antibody. Massive inflammatory cell infiltration was observed in samples from patients with CS (A, B), myocarditis (D, E), or other cardiomyopathies (G, H). Positive P. acnes immunostaining in macrophages of these inflammatory foci was detected only in samples from patients with CS (C; black arrows), and not in samples from those with myocarditis (F) or other cardiomyopathies (I). Original magnification; ×200 (left), ×1000 (middle and right).