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Proteome profiling in IL-1β and VEGF-activated human umbilical vein endothelial cells delineates the interlink between inflammation and angiogenesis

Fig 3

Venn diagrams and heat maps of the proteins detected HUVEC.

Venn diagrams are displayed for untreated HUVEC (green circles), HUVEC treated with 10ng/mL IL-1β (red circles) and HUVEC treated with 10ng/mL VEGF (blue circles). (A) cytoplasm fraction, (B) nucleic fraction, (C) extracellular fraction, (D) reanalysis of E-GEOD-10778 (IL-1β and VEGF stimulated HUVEC, mRNA of genes regulated by IL-1β or VEGF stimulation, red = upregulated, blue = downregulated) and (E) corresponding protein expression (red = expression level, grey = not detected).

Fig 3

doi: https://doi.org/10.1371/journal.pone.0179065.g003