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Stably engineered nanobubbles and ultrasound - An effective platform for enhanced macromolecular delivery to representative cells of the retina

Fig 5

Sample confocal microscopy images of ARPE-19 cells administered (A) antibody only and (D) antibody in the presence of ultrasound and nanobubbles; MIO-M1 cells administered (B) antibody only and (E) antibody in the presence of ultrasound and nanobubbles; 661W cells administered (C) antibody only and (F) antibody in the presence of ultrasound and nanobubbles.

Arrows indicate a cell in which antibody uptake (red) was observed. Scale bar = 20 μm.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0178305.g005