Controlled delivery of tauroursodeoxycholic acid from biodegradable microspheres slows retinal degeneration and vision loss in P23H rats
Fig 2
Electroretinographic responses in vehicle- and TUDCA-PLGA-MSs-treated eyes.
Representative scotopic ERG traces from postnatal days P30 (A), P60 (B), P90 (C) and P120 (D) P23H rats treated with unloaded PLGA microspheres (left, control) or microspheres containing TUDCA (right, TUDCA). Units to the left of the panels indicate the flash luminance in log cd·s/m2. Note that ERG responses reached higher values in eyes treated with TUDCA-PLGA MSs, as compared to vehicle-treated eyes.