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Adenosine A1 receptor activation increases myocardial protein S-nitrosothiols and elicits protection from ischemia-reperfusion injury in male and female hearts

Fig 6

Label-free SNO protein levels for various targets.

For common SNO proteins that were identified in male and female hearts, SNO levels were assessed via label-free peptide quantification for (A) aconitase, (B) electron transfer flavoprotein β, (C) lactate dehydrogenase, (D) voltage-dependent anion channel 2, (E) voltage-dependent anion channel 3, (F) isocitrate dehydrogenase α, (G) enoyl-CoA hydratase, and (H) sarcoplasmic reticulum Ca2+-ATPase 2a (male control: clear bar, male CHA: clear hashed bar, female control: black bar, female CHA: black hashed bar). Please note that for groups that do not contain a bar, the SNO peptide indicated was not detected.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0177315.g006