Water permeation through the internal water pathway in activated GPCR rhodopsin
Fig 3
Configuration of the solvent pore on the cytoplasmic side with ribbon representation of the Meta II structure.
Extracted 16 trajectories of water molecules that passed through the solvent pore are shown in different colors. Residues of the NPxxY are shown as purple and in the red circle. The retinal is shown in orange VDW format. (a) Close-up view of the first narrow region and (b) the second region are shown. Only five trajectories are shown. The first narrow region comprises L128, M257, and Y306, and the second narrow region comprises F261 and Y306.