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Characterization of a novel antibiofilm effect of nitric oxide-releasing aspirin (NCX-4040) on Candida albicans isolates from denture stomatitis patients

Fig 6

Nitric Oxide scavenger prevents NO-ASA antibiofilm effect.

Biofilms were pretreated with 200 μM carboxy-PTIO for 20 min at 37°C. Then NO-ASA 250 μM or 1 mM was added and biofilms were incubated for 24h at 37°C. Bars represent mean ± SD of biofilm formation quantified trough XTT reduction assay. * p<0.05; ** p<0.01; *** p>0.001; ****p>0.0001 as compared with control (DMSO). †p<0.05; ††p<0.01; ††† p>0.001; ††††p>0.0001 as compared between groups as indicated (one way ANOVA).

Fig 6

doi: https://doi.org/10.1371/journal.pone.0176755.g006