Semaphorin 3F expression is reduced in pregnancy complicated by preeclampsia. An observational clinical study
Fig 2
Semaphorin 3F and NRP2 protein expression in placental tissues.
Semaphorin 3F (A) and NRP2 (B) protein expression was analyzed by immunoblotting in placental tissues from both normal and preeclamptic subjects. Semaphorin 3F and NRP2 protein expression was significantly higher in normal placentae as compared to preeclamptic placentae. Quantification of semaphorin 3F and NRP2 protein expression is normalized to β-actin bands intensity. Data are represented as mean semaphorin 3F/β-actin and NRP2/β-actin ratio ± SD and are representative of the whole preeclampsia group and of 19 randomly selected women from the control group. (*) p = 0.04 for Semaphorin 3F and p = 0.03 for NRP2, respectively.