A genome-wide trans-ethnic interaction study links the PIGR-FCAMR locus to coronary atherosclerosis via interactions between genetic variants and residential exposure to traffic
Fig 4
Manhattan Plot of Interaction P-values for AA GWIS.
Though no interactions exceeded the genome-wide significance threshold a cluster of SNP-by-TRAP interactions on chromosome 1 (FCAMR-PIGR locus) exceeded the threshold for suggestive evidence of association (P < 1x10-5, blue line).