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Multimodal MR-imaging reveals large-scale structural and functional connectivity changes in profound early blindness

Fig 4

Correlation between white matter structural (obtained by HARDI) and resting state (obtained by rsfcMRI) functional connectivities.

A) Scatter plot depicting the degree of association characterizing white matter structural (upper panel) and resting state functional (lower panel) connectivity between early blind and sighted controls. The measure of association (Pearson’s coefficient) was found to be highly significant (p<0.0001) for both white matter structural connectivity and resting state functional connectivity (r = 0.9512 and r = 0.8623, respectively). B) Scatter plot depicting correlations on all t-statistics of early blind compared to sighted controls for both white matter structural connectivity (HARDI fiber number) and functional connectivity (resting state partial correlations). Associating relative changes in white matter and functional connectivity between early blind and sighted controls were not statistically significant (r = -0.008, p>0.05).

Fig 4

doi: https://doi.org/10.1371/journal.pone.0173064.g004