Impact of genetic variation on three dimensional structure and function of proteins
Fig 1
Distribution of SNVs based on structural position.
A. Distribution of the SNVs in our benchmark dataset based on structural position (Piechart). There are two broad categories, Surface (residue) or Buried (residue). B. Distribution of the SNVs in the dataset based on secondary structural location (Bar graph). The two broad categories, Surface (residue) or Buried (residue) are further categorized into Loop, Alpha_helix and Beta_strand based on the secondary structural element to which the SNV maps.