Neuronal Cell Death and Degeneration through Increased Nitroxidative Stress and Tau Phosphorylation in HIV-1 Transgenic Rats
Fig 8
Increased oxidative stress, NADPH oxidase and CYP2E1 in the hippocampus of HIV-1 Tg rats.
(A, B) Plasma ROS levels (A) and hippocampal NADPH oxidase activity in WT and HIV-1 Tg rats (n = 4/group), *P < 0.05. (C) Representative immunoblots of hippocampal lysates from WT and HIV-1 Tg rats with the specific antibody to CYP2E1, CYP4A, or GAPDH, as indicated. Densitometric quantitation of each indicated protein relative to GAPDH is also shown (n = 4/group), *P < 0.05.