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Resveratrol Impairs Glioma Stem Cells Proliferation and Motility by Modulating the Wnt Signaling Pathway

Fig 4

RSV reduced GSC motility.

The migration ability of GSCs was investigated by Wound healing assay. Monolayers of growth-arrested GSCs were scraped and treated with different concentrations of RSV for 48, 72 and 96 hs. (A) Representative images were taken at different time points to evaluate wound closure. (B) The migration was quantified by means of the TScratch software and results are reported as percentages over control values and calculated as the wound area at a given time compared to the initial wound surface. Bars represent SEM.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0169854.g004