The CCL2/CCR2 Axis Affects Transmigration and Proliferation but Not Resistance to Chemotherapy of Acute Myeloid Leukemia Cells
Fig 2
Expression of CCR2 by AML patient samples.
(A) Leukemia blasts purified from BM primary samples were analyzed for CCR2 expression by FCM. (B) Patient 2 BM FCM analysis (histogram) is shown as an example with 56% CCR2+ leukemia cells. (C) Leukemia blasts purified from PB primary samples were analyzed for CCR2 expression by FCM. (D) Patient 2 PB FCM analysis (histogram) is shown as an example with 53% CCR2+ leukemia cells. (F) Overall analysis of CCR2 expression profile by qPCR from all BM patient samples compared to positive control. Positive control sample corresponds to a BM sample from a healthy donor with 5% normal monocytes.