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Modulation of Type-1 and Type-2 Cannabinoid Receptors by Saffron in a Rat Model of Retinal Neurodegeneration

Fig 4

CB1 and CB2 protein levels following saffron treatment and BCL exposure.

(A) Representative Western blot of CB1 and CB2 in the retinas from controls, rats exposed to bright continuous light alone (LD), or in combination with saffron (saffron + LD). Panel B shows densitometry of CB1 and CB2 expression normalised for its own control. Data were expressed as means ± SEM (n = 6), and were analyzed by one-way analysis of variance (ANOVA) followed by Bonferroni post hoc analysis.*p<0.05 vs control, ##p<0.01 vs LD.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0166827.g004