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LIGHT (TNFSF14) Increases the Survival and Proliferation of Human Bone Marrow-Derived Mesenchymal Stem Cells

Fig 1

Characterization of bone marrow-derived MSCs (BM-MSCs).

(A) Negative marker (CD34, CD45, and CD19) staining in BM-MSCs. (B) Positive marker (CD90, CD44, and CD105) staining in BM-MSCs. The level of expression of each marker was determined by FACS analysis. Filled histogram represents the isotype control (mouse IgG); open histogram represents each antigen. (C) Representative images of cells such as adipocytes, chondrocytes, and osteocytes undergoing differentiation via adipogenesis (Oil Red O staining), chondrogenesis (Alcian blue staining), and osteogenesis (Alizarin red staining), respectively. MSCs, mesenchymal stromal cells, MSCs; BM-MSCs, bone marrow-derived MSCs; P, passage number.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0166589.g001