The Effects of Dietary Macronutrient Balance on Skin Structure in Aging Male and Female Mice
Fig 6
Macronutrient intake influences subcutaneous fat.
Response surfaces showing the association of macronutrient intake (protein, carbohydrate and fat in kJ/d) on subcutaneous adipocyte size (μm2) and adipocyte numbers (cells/105μm2). (a-c) male adipocytes become grossly enlarged with high fat intake whist adipocytes proliferate with high protein intake (d-f; cells/105μm2). (g-i) female adipocytes enlarge to a lesser extent than male adipocytes with high carbohydrate or fat intake and proliferate with increasing protein intake (j-i). For each 2D slice, the third factor is at its median. The red line indicates the ratio of macronutrients that minimizes each response. (see also S4 Table)