Direct Stimulation of Islet Insulin Secretion by Glycolytic and Mitochondrial Metabolites in KCl-Depolarized Islets
Table 2
Measurement of ATP production by islets depolarized with 70 mM KCl: islet ATP content and its accumulation in the extracellular medium in response to addition of the indicated citric acid cycle intermediate and its corresponding cofactors for the pyruvate/malate or isocitrate/malate cycles. Effect of 10μM antimycin A.
The experimental conditions were the same as described above in the legend of Table 1. (More information is found in Materials and Methods section).