Involvement of Macrophages in the Pathogenesis of Familial Amyloid Polyneuropathy and Efficacy of Human iPS Cell-Derived Macrophages in Its Treatment
Fig 4
Morphology and expression of inhibitory macrophage markers in iPS-MLs.
(A) iPS-ML morphology is shown. (B) Flow cytometry analysis shows expression of myeloid markers including CD45, CD33, CD14, and CD11b on iPS-MLs. Inhibitory macrophage markers, CD163 and CD206, were identified on iPS-MLs. Staining profiles of specific (black areas) and isotype-matched control (gray lines) monoclonal antibodies are shown. Data are representative of three independent experiments. Scale bars: 100 μm.