An Experimental Model of Vasovagal Syncope Induces Cerebral Hypoperfusion and Fainting-Like Behavior in Awake Rats
Fig 1
Effects of Various Sets of Stimulation Parameters on HR, MAP, and CBF.
A representative plot of the stimulator current (mA), heart rate (BPM), mean arterial pressure (mmHg), and cerebral blood flow (perfusion units) is shown. Baseline data was collected for 4 minutes before beginning stimulation (minutes 0–4). Five minutes of recovery was allowed after each stimulation event. Stimulation occurred for 3 minutes using eight different sets of stimulation parameters: 2 mA at 0.025 Hz (I), 4 mA at 0.025 Hz (II), 2 mA at 0.05 Hz (III), 4 mA at 0.05 Hz (IV), 2 mA at 0.1 Hz (V), 4 mA at 0.1 Hz (VI), 2 mA at 0.5 Hz (VII), and 4 mA at 0.5 Hz (VIII). Red lines highlight the start and stop of each stimulation event. The greatest drop in CBF (13.9%) occurred for the 4 mA, 0.025 Hz current (II).