Immunogenicity and Lupus-Like Autoantibody Production Can Be Linked to Each Other along With Type I Interferon Production in Patients with Rheumatoid Arthritis Treated With Infliximab: A Retrospective Study of a Single Center Cohort
Fig 1
Anti-drug antibody (ADA) is associated with reduced clinical response.
(A) Treatment efficacy defined as low disease activity (LDA) or remission at 6 months. Percentages and absolute numbers of each group of patients are indicated below the graphs. ADA positivity was based on the assessment of 6 months. Fisher’s exact test was used for comparison. (B) Cumulative drug retention rates. A log-rank test was used for comparison between the two groups.