Acteoside Binds to Caspase-3 and Exerts Neuroprotection in the Rotenone Rat Model of Parkinson's Disease
Fig 1
Acteoside attenuates rotenone-induced α-synuclein, caspase-3 upregulation and MAP2 downregulation in rats.
Immunohistochemistry (IHC) for α-synuclein in A) the control group, B) the rotenone PD model group and C) plus acteoside treatment group. D) The expression levels of α-synuclein. a: P<0.01 compared to control and b: P<0.01 compared to the model. E) Expression levels of MAP2. F) Western blot assay for caspase-3. G) Expression levels of caspase-3 in the control, PD model and acteoside treatment (“Treatment”) groups: a: P<0.01 compare to control and b: P<0.01 compare to PD model.