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Atopy and Inhaled Corticosteroid Use Associate with Fewer IL-17+ Cells in Asthmatic Airways

Fig 4

IL-17 expression in the submucosa of bronchial biopsies of 4 groups of studied population.

atopic inhaled corticosteroid (ICS) user (frame A), nonatopic ICS user (frame B), atopic non-ICS user (frame C), nonatopic non-ICS user (frame D). Single staining for IL-17 (frame E; blue) and MPO (frame F; red) and double staining for IL-17 and MPO (frame G; purple) in adjacent sections of a nonatopic non-ICS user asthmatic patient. Single staining for IL-17 (frame H; blue) and EPX (frame I; red) and double staining for IL-17 and EPX (frame J; purple) in adjacent sections of an atopic non-ICS user asthmatic patient.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0161433.g004