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Plasma Prostaglandin E2 Levels Correlated with the Prevention of Intravenous Immunoglobulin Resistance and Coronary Artery Lesions Formation via CD40L in Kawasaki Disease

Fig 5

IVIG inhibition of CD40L expression on CD4+ T cells.

Greater concentrations (250 mg/dL and 2500 mg/dL) of IVIG significantly inhibited CD40L expression on CD4+ T cells after 24 hours of treatment.*p < 0.05 compared to the average. Data are presented as mean ± standard error. All tests were separately carried out three times each (N = 4).

Fig 5

doi: https://doi.org/10.1371/journal.pone.0161265.g005