Hyperglycemia Determines Increased Specific MicroRNAs Levels in Sera and HDL of Acute Coronary Syndrome Patients and Stimulates MicroRNAs Production in Human Macrophages
Fig 2
Distribution of analyzed miRNAs in HDL subfractions: HDL2 (A) and HDL3 (B) isolated by density gradient ultracentrifugation from pooled sera obtained from coronary artery disease (CAD) patients with stable angina (SA) and acute coronary syndrome (ACS), with/without hyperglycemia; the procedure was performed on 3 pools of sera from each group. Data are expressed as mean 2-ΔCq values multiplied by 106 ± standard error of the mean (* p<0.05, ** p<0.01, *** p<0.001 hyperglycemic (HG) vs. normoglycemic (NG), Student T-test).