Cyclophilin Inhibitors Remodel the Endoplasmic Reticulum of HCV-Infected Cells in a Unique Pattern Rendering Cells Impervious to a Reinfection
Fig 2
All CypI tested greatly alter the organization of the ER of HCV-infected cells.
Same as Fig 1 except that two additional CypI were used—the immunosuppressive CypI CsA and the non-immunosuppressive CypI CPI-431-32. N = Nucleus; MW = membranous web; and * = distended ER. Images are representative of more than 3 independent experiments.