Asymmetric Cancer Hallmarks in Breast Tumors on Different Sides of the Body
Fig 1
Hallmarks of Cancer selected for the study.
Five of the six cancer hallmarks proposed by Hanahan and Weinberg were selected for this study: i.e. Sustained proliferative signaling (CH1), Evasion of growth suppressors (CH2), Resistance to cell death (CH3), Induction of angiogenesis (CH4) and Activation of invasion and metastasis (CH6) The Hanahan-Weinberg hallmark “Enabled replicative immortality” is replaced in this study by “Genome instability” (CH5) as an alternative hallmark. The number of genes participating in the CH are shown each ellipse.