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Understanding and Controlling Sialylation in a CHO Fc-Fusion Process

Fig 6

N-Glycan Structures.

The N-glycan assay method quantifies the percent distribution of N-glycan species. Five key structures were quantified in samples generated from 5-L bioreactors were operated under normal (50%) and low (15%) DO conditions. G0F, G1F and G2F are unsialylated, S1G1F is monosialylated, and S2G2F is disialylated.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0157111.g006