Distinct BOLD fMRI Responses of Capsaicin-Induced Thermal Sensation Reveal Pain-Related Brain Activation in Nonhuman Primates
Fig 5
Inter-subject difference in activated brain volume potentiated by the application of capsaicin or vehicle.
Differences in activated brain volume measured from individual animals, elucidating the inter-subject variability of the capsaicin effect, where red represents an increase in activated brain volume after the capsaicin application and green represents the opposite. As shown, increases in activated brain volume after the capsaicin application can be found in most animals (6 out of 8) whilst the vehicle application did not elicit robust alterations for most animals.