The Regulation of para-Nitrophenol Degradation in Pseudomonas putida DLL-E4
Fig 5
Differential expression of genes involved in upstream central carbon metabolism and PNP catabolism according to the comparative transcriptome analysis.
The biochemical network schematically sketches the main bioreactions involved in C processing and PNP hydrolysis. The conditions mentioned in this figure are identical to the previous conditions used for the RNA-Seq samples (E4-GP vs E4-G, and R-GP vs R-G, as described in the legend to Fig 1). Genes encoding enzymes involved in these bioreactions are highlighted in different colors according to whether they were significantly upregulated (red) or downregulated (green). The red heavy arrow represents that glucose utilization could be enhanced when PNP was present. The blue heavy arrow represents that glucose prompts the degradation of PNP. The black heavy double-arrow indicates that PNP degradation and glucose catabolism are regulated by carbon catabolite repression.