Role of HIF1A, VEGFA and VEGFR2 SNPs in the Susceptibility and Progression of COPD in a Spanish Population
Fig 1
Lung function differences between rs3025020 genotypes in patients with Chronic Obstructive Pulmonary Disease over time.
FEV1 (% pred) for the three genotypes of SNP rs3025020 (VEGFA gene) over time. The presence of allele T in homozygosis determined higher values of FEV1 (% pred) respect to the other genotypes. The differences remained constant for every visit (** p-value<0.01; *** p-value<0.001) and along 3 years of follow-up (p = 0.017). The sample size for each moment was: Baseline: N = 132; 1st year: N = 118; 2nd year: N = 98 and 3rd year: N = 87.